Silver or gold nanoparticles for biosensors ?

The particular sensitivity of the surface plasmon resonance (SPR) to changes in the local environment of nanoparticles (NPs), allows their use as platforms to probe chemical and biochemical binding events on their surfaces without any labeling. We performed a comparative study of gold and silver NPs based biosensors, prepared within the same conditions, in order to determine which one seems the best for biological sensing. Our results attest the superiority of Ag NPs over Au ones. Indeed, Ag NPs exhibit a more intense SPR band than gold NPs. Moreover, the Ag SPR band is more sensitive to the environment modifications. These two properties allow the detection of a lower concentration of target species when functionalized Ag NPs are used instead of gold ones.

Reference: M. Lismont and L. Dreesen, Mat. Sci. Eng. C, in press (2012)


About nicovdw

Professor in Physics
This entry was posted in Article and tagged , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s